Mouse Cyth2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cyth2
Locus ID	19158
Kit Components	GA203420G1, Cyth2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203420G2, Cyth2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203420G3, Cyth2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001112701, NM_011181
Synonyms	ARNO; CLM2; Pscd2
Summary	Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (PubMed:18042453). The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (PubMed:25326380).[UniProtKB/Swiss-Prot Function]

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