Mouse Ppp1r1b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ppp1r1b
Locus ID	19049
Kit Components	GA203356G1, Ppp1r1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203356G2, Ppp1r1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203356G3, Ppp1r1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144828
Synonyms	AU040756; DARPP-32; Darpp32
Summary	This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders in humans. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

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