Mouse Polb activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Polb
Locus ID	18970
Kit Components	GA203316G1, Polb gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203316G2, Polb gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203316G3, Polb gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011130
Synonyms	A430088C08Rik
Summary	Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity).[UniProtKB/Swiss-Prot Function]

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