Mouse Bloc1s6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bloc1s6
Locus ID	18457
Kit Components	GA203085G1, Bloc1s6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203085G2, Bloc1s6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203085G3, Bloc1s6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019788
Synonyms	BLOC-1; pa; Pldn; Stx13bp1
Summary	Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.[UniProtKB/Swiss-Prot Function]

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