Mouse Osm activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Osm
Locus ID	18413
Kit Components	GA203063G1, Osm gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203063G2, Osm gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203063G3, Osm gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001013365
Synonyms	OncoM
Summary	Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity). Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).[UniProtKB/Swiss-Prot Function]

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