Mouse Fxyd5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fxyd5
Locus ID	18301
Kit Components	GA203013G1, Fxyd5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203013G2, Fxyd5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203013G3, Fxyd5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111073, NM_001287213, NM_001287217, NM_008761
Synonyms	EF-8; Oit2; RIC
Summary	This gene encodes a precursor protein that is member of the FXYD family of transmembrane glycoproteins. Like most members of the FXYD family, the encoded protein is a subunit of the sodium-potassium adenosine triphosphatase pump. FXYD family members have tissue-specific expression and differentially regulate the activity of this pump. The protein encoded by this gene also plays a role in cell adhesion and motility. The orthologous human protein inhibits epithelial cadherin, a calcium-dependent adhesion protein and is associated with cancer (promotes metastasis). Alternative splicing of this mouse gene results in multiple transcript variants. [provided by RefSeq, Dec 2013]

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