Mouse Oc90 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Oc90
Locus ID	18256
Kit Components	GA203002G1, Oc90 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203002G2, Oc90 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203002G3, Oc90 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347038, NM_010953
Synonyms	oc95; Ocn-95; PLA2L; Pla2ll
Summary	Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear (PubMed:17300776). Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure (PubMed:21655225, PubMed:24748133). Together with OTOL1, modulates calcite crystal morphology and growth kinetics (PubMed:24748133). It is unlikely that this protein has phospholipase A2 activity (PubMed:17300776).[UniProtKB/Swiss-Prot Function]

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