Mouse Nup62 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nup62
Locus ID	18226
Kit Components	GA202995G1, Nup62 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202995G2, Nup62 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202995G3, Nup62 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_053074
Synonyms	D7Ertd649e; Nupc1; p62
Summary	Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown.[UniProtKB/Swiss-Prot Function]

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