Mouse Ntrk3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ntrk3
Locus ID	18213
Kit Components	GA202987G1, Ntrk3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202987G2, Ntrk3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202987G3, Ntrk3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008746, NM_182809
Synonyms	AW125844; Ntrk3_tv3; TrkC
Summary	Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.[UniProtKB/Swiss-Prot Function]

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