Mouse Ntf3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ntf3
Locus ID	18205
Kit Components	GA202982G1, Ntf3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202982G2, Ntf3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202982G3, Ntf3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164034, NM_001164035, NM_008742
Synonyms	AI316846; AI835689; HDNF; NGF-2; Nt3; Ntf-3
Summary	This gene encodes a member of the neurotrophins that have a wide variety of functions in both neural and non-neural tissues. The encoded preproprotein undergoes proteolytic processing to generate a noncovalently linked homodimeric mature protein that can bind to the transmembrane receptor tyrosine kinases to initiate a series of signaling events. Mice lacking the encoded protein exhibit severe defects in the peripheral nervous system including a complete lack of spinal proprioceptive afferents and their peripheral sense organs. [provided by RefSeq, Sep 2016]

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