Mouse Nog activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nog
Locus ID	18121
Kit Components	GA202931G1, Nog gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202931G2, Nog gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202931G3, Nog gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008711
Summary	Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738). Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity).[UniProtKB/Swiss-Prot Function]

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