Mouse Nkx2-2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nkx2-2
Locus ID	18088
Kit Components	GA202908G1, Nkx2-2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202908G2, Nkx2-2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202908G3, Nkx2-2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001077632, NM_010919
Synonyms	Nkx-2.2; Nkx2.2; tinman
Summary	Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (PubMed:11076772). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (PubMed:19759004).[UniProtKB/Swiss-Prot Function]

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