Mouse Nin activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nin
Locus ID	18080
Kit Components	GA202904G1, Nin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202904G2, Nin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202904G3, Nin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081453, NM_001286079, NM_001286080, NM_008697, NR_104397, NR_104398
Synonyms	3110068G20Rik; AI385615; AU024711; mKIAA1565
Summary	Centrosomal protein required for the positioning and anchorage of the microtubule minus-end in epithelial cells (PubMed:15784680, PubMed:10934040). May also act as a centrosome maturation factor (By similarity). May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome (PubMed:15784680). Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules (By similarity). Required for centriole organization and microtubule anchoring at the mother centriole (By similarity).[UniProtKB/Swiss-Prot Function]

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