Mouse Nfya activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nfya
Locus ID	18044
Kit Components	GA202892G1, Nfya gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202892G2, Nfya gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202892G3, Nfya gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001110832, NM_001347401, NM_001347402, NM_010913
Synonyms	AA407810; Cbf-b; SEZ-10; SEZ10
Summary	Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.[UniProtKB/Swiss-Prot Function]

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