Mouse Nfix activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nfix
Locus ID	18032
Kit Components	GA202882G1, Nfix gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202882G2, Nfix gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202882G3, Nfix gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081981, NM_001081982, NM_001297601, NM_010906
Synonyms	CTF; NF-I/X; NF1-X; NFI-X
Summary	Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Isoform NFIX1 acts as a transcriptional activator while isoform NFIX3 acts as a repressor.[UniProtKB/Swiss-Prot Function]

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