Mouse Ndn activation kit by CRISPRa

CAT#: GA202846

Ndn CRISPRa kit - CRISPR gene activation of mouse necdin



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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NDN Antibody - C-terminal region
    • 100 ul

CNY 5250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Ndn
Locus ID 17984
Kit Components

GA202846G1, Ndn gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202846G2, Ndn gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202846G3, Ndn gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_010882
Synonyms AI528698; Peg6
Summary Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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