Mouse Naip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Naip1
Locus ID	17940
Kit Components	GA202824G1, Naip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202824G2, Naip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202824G3, Naip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008670
Synonyms	AV364616; Birc1a; D13Lsd1; Naip; Naip-rs1
Summary	Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor-neuron apoptosis induced by a variety of signals (By similarity).[UniProtKB/Swiss-Prot Function]

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