Mouse Msl3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Msl3
Locus ID	17692
Kit Components	GA202724G1, Msl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202724G2, Msl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202724G3, Msl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010832, NM_001370791, NM_001370792, NM_001370793, NM_001370794, NM_001370795, NM_001370796, NM_001370797, NM_001370798, NM_001370799
Synonyms	AU018931; Msl3l1; Msl31
Summary	Has a role in chromatin remodeling and transcriptional regulation. Has a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.[UniProtKB/Swiss-Prot Function]

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