Mouse Mmp16 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mmp16
Locus ID	17389
Kit Components	GA202680G1, Mmp16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202680G2, Mmp16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202680G3, Mmp16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019724, NR_135158
Synonyms	MT-MMP 3; MT3-MMP; Mt3mmp
Summary	This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit retarded growth of the skeleton, especially in the cranium and long bones. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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