Mouse Mmp14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mmp14
Locus ID	17387
Kit Components	GA202678G1, Mmp14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202678G2, Mmp14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202678G3, Mmp14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008608
Synonyms	AI325305; MMP-X1; MT-MMP-1; MT1-MMP; sabe
Summary	This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit craniofacial dysmorphism, arthritis, osteopenia, dwarfism, and fibrosis of soft tissues. [provided by RefSeq, Feb 2016]

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