Mouse Afdn activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Afdn
Locus ID	17356
Kit Components	GA202670G1, Afdn gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202670G2, Afdn gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202670G3, Afdn gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010806, NR_151731
Synonyms	5033403D15Rik; Af-6; AF6; Afadin; Gm314; I-afadin; Mllt4; S-afadin
Summary	Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm.[UniProtKB/Swiss-Prot Function]

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