Mouse Mgmt activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mgmt
Locus ID	17314
Kit Components	GA202654G1, Mgmt gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202654G2, Mgmt gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202654G3, Mgmt gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008598
Synonyms	Agat; AGT; AI267024
Summary	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.[UniProtKB/Swiss-Prot Function]

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