Mouse Mef2d activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mef2d
Locus ID	17261
Kit Components	GA202631G1, Mef2d gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202631G2, Mef2d gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202631G3, Mef2d gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001310587, NM_001310593, NM_133665, NM_197994
Synonyms	C80750
Summary	Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.[UniProtKB/Swiss-Prot Function]

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