Mouse Anapc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Anapc1
Locus ID	17222
Kit Components	GA202610G1, Anapc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202610G2, Anapc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202610G3, Anapc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008569
Synonyms	2610021O03Rik; AI047775; AI853536; Apc1; AW547281; Mcpr; tsg24
Summary	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).[UniProtKB/Swiss-Prot Function]

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