Mouse Mcl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mcl1
Locus ID	17210
Kit Components	GA202602G1, Mcl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202602G2, Mcl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202602G3, Mcl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008562
Synonyms	AW556805; Mcl-1
Summary	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 2 has antiapoptotic activity.[UniProtKB/Swiss-Prot Function]

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