Mouse Ly96 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ly96
Locus ID	17087
Kit Components	GA202529G1, Ly96 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202529G2, Ly96 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202529G3, Ly96 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159711, NM_016923
Synonyms	ESOP-1; MD-2; MD2
Summary	Binds bacterial lipopolysaccharide (LPS) (PubMed:22532668). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10725698).[UniProtKB/Swiss-Prot Function]

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