Mouse Ltbp3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ltbp3
Locus ID	16998
Kit Components	GA202509G1, Ltbp3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202509G2, Ltbp3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202509G3, Ltbp3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008520
Synonyms	Ltbp2; mFLJ00070
Summary	Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.[UniProtKB/Swiss-Prot Function]

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