Mouse Lipa activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lipa
Locus ID	16889
Kit Components	GA202464G1, Lipa gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202464G2, Lipa gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202464G3, Lipa gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111100, NM_021460
Synonyms	AA960673; Lal; Lip-1; Lip1
Summary	Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation (By similarity).[UniProtKB/Swiss-Prot Function]

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