Mouse Lbp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lbp
Locus ID	16803
Kit Components	GA202422G1, Lbp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202422G2, Lbp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202422G3, Lbp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008489
Synonyms	Bpifd2; Ly88
Summary	Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:9144073). Acts as an affinity enhancer for CD14, facilitating its association with LPS (By similarity). Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:24380872).[UniProtKB/Swiss-Prot Function]

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