Mouse Ksr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ksr1
Locus ID	16706
Kit Components	GA202392G1, Ksr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202392G2, Ksr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202392G3, Ksr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001348207, NM_013571
Synonyms	AW492498; B-KSR1; D11Bhm183e; D11Bhm184e; hb; Ksr; mKSR1; RSU2
Summary	Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases (PubMed:10409742, PubMed:12932319, PubMed:21102438). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (PubMed:21102438). Does not have kinase activity by itself (Probable).[UniProtKB/Swiss-Prot Function]

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