Mouse Kif3a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kif3a
Locus ID	16568
Kit Components	GA202306G1, Kif3a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202306G2, Kif3a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202306G3, Kif3a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290805, NM_001290806, NM_008443
Synonyms	Kif3; Kifl; Kns3
Summary	Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation (PubMed:21670265). Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitement of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole (PubMed:23386061).[UniProtKB/Swiss-Prot Function]

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