Mouse Kif16b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kif16b
Locus ID	16558
Kit Components	GA202298G1, Kif16b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202298G2, Kif16b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202298G3, Kif16b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081133, NM_001355123
Synonyms	8430434E15Rik; AA623607; AI789011; C80253; C80902; mKIAA1590
Summary	Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.[UniProtKB/Swiss-Prot Function]

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