Mouse Kcnu1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kcnu1
Locus ID	16532
Kit Components	GA202281G1, Kcnu1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202281G2, Kcnu1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202281G3, Kcnu1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008432
Synonyms	Kcnma3; mSlo3; Slo3
Summary	Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.[UniProtKB/Swiss-Prot Function]

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