Mouse Il18rap activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il18rap
Locus ID	16174
Kit Components	GA202131G1, Il18rap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202131G2, Il18rap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202131G3, Il18rap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010553
Synonyms	AcPL; IL-1RAcPL; IL-18R-beta; IL-18RAcP; IL-18Rbeta
Summary	Interleukin-18 (or interferon-gamma inducing factor) is a proinflammatory cytokine that induces cell-mediated immunity following microbial infection. This gene encodes a member of the interleukin-1 receptor family. The encoded protein is an accessory subunit of the receptor for interleukin-18 and mediates signaling through this cytokine. Mice lacking this gene exhibit a defective cell-mediated immune response. [provided by RefSeq, Jan 2014]

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