Mouse Il15ra activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il15ra
Locus ID	16169
Kit Components	GA202126G1, Il15ra gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202126G2, Il15ra gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202126G3, Il15ra gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271497, NM_001271498, NM_001271499, NM_001271500, NM_001271501, NM_008358, NM_133836, NR_073191, NR_073192
Synonyms	AA690181; IL-15RA
Summary	High-affinity receptor for interleukin-15 (PubMed:17947230). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (PubMed:17947230). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (By similarity). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (By similarity).[UniProtKB/Swiss-Prot Function]

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