Mouse Ifnar2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ifnar2
Locus ID	15976
Kit Components	GA202079G1, Ifnar2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202079G2, Ifnar2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202079G3, Ifnar2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001110498, NM_001347258, NM_010509
Synonyms	AI747302; Ifnar-2
Summary	Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and isoform 3 may be potent inhibitors of type I IFN receptor activity.[UniProtKB/Swiss-Prot Function]

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