Mouse Irf8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irf8
Locus ID	15900
Kit Components	GA202050G1, Irf8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202050G2, Irf8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202050G3, Irf8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001301811, NM_008320
Synonyms	AI893568; ICSBP; Icsbp1; IRF-8; Myls
Summary	The protein encoded by this gene is a transcription factor that belongs to the interferon regulatory factor family. Proteins belonging to this family have a DNA binding domain at the amino terminus that contains five well-conserved tryptophan-rich repeats. This domain recognizes DNA sequences similar to the interferon-stimulated response element. The protein encoded by this gene promotes or suppresses lineage-specific genes to regulate the differentation of lymphoid and myeloid lineage cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

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