Mouse Tfb2m activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tfb2m
Locus ID	15278
Kit Components	GA201910G1, Tfb2m gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201910G2, Tfb2m gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201910G3, Tfb2m gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001331054, NM_001331055, NM_008249
Synonyms	Hkp1
Summary	S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.[UniProtKB/Swiss-Prot Function]

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