Mouse H2ax activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	H2ax
Locus ID	15270
Kit Components	GA201906G1, H2ax gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201906G2, H2ax gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201906G3, H2ax gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010436
Synonyms	AW228881; gammaH2ax; H2A.X; H2ax; Hist5-2ax
Summary	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. [provided by RefSeq, Nov 2015]

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