Mouse Hira activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hira
Locus ID	15260
Kit Components	GA201904G1, Hira gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201904G2, Hira gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201904G3, Hira gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010435, NM_001005228
Synonyms	AA138857; D16Ertd95e; Gm15797; N28177; OTTMUSG00000026264; Tuple1
Summary	Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.[UniProtKB/Swiss-Prot Function]

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