Mouse Hhex activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hhex
Locus ID	15242
Kit Components	GA201895G1, Hhex gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201895G2, Hhex gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201895G3, Hhex gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008245
Synonyms	Hex; Hex1; Hhex-rs2; Prh; Prhx
Summary	Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.[UniProtKB/Swiss-Prot Function]

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