Mouse Mr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mr1
Locus ID	15064
Kit Components	GA201833G1, Mr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201833G2, Mr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201833G3, Mr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008209, NM_001355062, NM_001355063
Synonyms	H2ls
Summary	Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites (By similarity). Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.[UniProtKB/Swiss-Prot Function]

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