Mouse Lancl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lancl1
Locus ID	14768
Kit Components	GA201710G1, Lancl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201710G2, Lancl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201710G3, Lancl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001190984, NM_001190985, NM_021295
Synonyms	AW124738; Gpr69; Gpr69a; p40
Summary	Functions as glutathione transferase (PubMed:25158856). Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate (PubMed:25158856). Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism (PubMed:25158856). May play a role in EPS8 signaling. Binds glutathione (By similarity).[UniProtKB/Swiss-Prot Function]

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