Mouse Gcnt1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gcnt1
Locus ID	14537
Kit Components	GA201571G1, Gcnt1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201571G2, Gcnt1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201571G3, Gcnt1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136484, NM_010265, NM_173442
Synonyms	5630400D21Rik; B130048E03; C2 GlcNAcT; C2GNT; IGnT
Summary	Glycosyltransferase that catalyzes the transfer of an N-acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O-glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes.[UniProtKB/Swiss-Prot Function]

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