Mouse Gata1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gata1
Locus ID	14460
Kit Components	GA201551G1, Gata1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201551G2, Gata1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201551G3, Gata1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008089
Synonyms	eryf1; Gata-1; Gf-1
Summary	Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (By similarity).[UniProtKB/Swiss-Prot Function]

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