Mouse Fpr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fpr1
Locus ID	14293
Kit Components	GA201470G1, Fpr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201470G2, Fpr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201470G3, Fpr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013521
Synonyms	fMLF-R; FPR; LXA4R
Summary	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity).[UniProtKB/Swiss-Prot Function]

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