Mouse Fcer1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fcer1a
Locus ID	14125
Kit Components	GA201371G1, Fcer1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201371G2, Fcer1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201371G3, Fcer1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010184
Synonyms	Fce1a; fcepsilonri; FcERI; Fcr-5
Summary	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.[UniProtKB/Swiss-Prot Function]

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