Mouse Fbn2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbn2
Locus ID	14119
Kit Components	GA201367G1, Fbn2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201367G2, Fbn2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201367G3, Fbn2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010181
Synonyms	BC063774; Fib-2; mKIAA4226; sne; sy
Summary	Fibrillin-2: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively (PubMed:20855508).[UniProtKB/Swiss-Prot Function]

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