Mouse Fscn1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fscn1
Locus ID	14086
Kit Components	GA201352G1, Fscn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201352G2, Fscn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201352G3, Fscn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007984
Synonyms	AI663989; Fan1; fascin-1
Summary	Actin-binding protein that contains 2 major actin binding sites (By similarity). Organizes filamentous actin into parallel bundles (PubMed:7738015). Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers (By similarity). Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (PubMed:21685497). Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF (By similarity).[UniProtKB/Swiss-Prot Function]

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