Mouse F7 activation kit by CRISPRa

CAT#: GA201341

F7 CRISPRa kit - CRISPR gene activation of mouse coagulation factor VII



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol F7
Locus ID 14068
Kit Components

GA201341G1, F7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201341G2, F7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201341G3, F7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_010172
Synonyms AI132620; Cf7; FVII
Summary This gene encodes a vitamin K-dependent serine protease that plays a critical role in the extrinsic pathway of blood coagulation. Upon contact with tissue factor III (TF III), the encoded protein forms an activated complex termed TF-FVIIa that initiates the coagulation cascade involving other coagulation factors, ultimately resulting in a fibrin clot. Complete lack of the encoded protein in mice results in in perinatal lethality due to bleeding from normal blood vessels. [provided by RefSeq, Apr 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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