Mouse F7 activation kit by CRISPRa
CAT#: GA201341
F7 CRISPRa kit - CRISPR gene activation of mouse coagulation factor VII
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | F7 |
Locus ID | 14068 |
Kit Components | GA201341G1, F7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201341G2, F7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201341G3, F7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_010172 |
Synonyms | AI132620; Cf7; FVII |
Summary | This gene encodes a vitamin K-dependent serine protease that plays a critical role in the extrinsic pathway of blood coagulation. Upon contact with tissue factor III (TF III), the encoded protein forms an activated complex termed TF-FVIIa that initiates the coagulation cascade involving other coagulation factors, ultimately resulting in a fibrin clot. Complete lack of the encoded protein in mice results in in perinatal lethality due to bleeding from normal blood vessels. [provided by RefSeq, Apr 2015] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN505478 | F7 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |